Tag: ciracas

Gambaran Faktor-Faktor Kejadian Infeksi Tuberkulosis Laten Di Rumah Tahanan Kelas I Bandung (Description of Latent Tuberculosis Infection Factors in Prison Class I Bandung)

Waworuntu, Fatimah

Latar belakang. Secara global, angka prevalensi tuberkulosis paru (TB) di rutan/lapas diketahui lebih tinggi dibandingkan dengan di populasi umum. Dengan kondisi yang padat dan fasilitas yang kurang memadai, rutan/lapas diduga merupakan tempat terjadinya penularan TB antar wargabinaan (WBP). Namun pengukuran tingkat prevalensi TB di rutan/lapas di Indonesia belum pernah dilakukan, dan sampai saat ini belum laporan yang komprehensif mengenai faktor risiko infeksi TB laten di rutan/lapas di Indonesia.
Tujuan penelitian. Penelitian ini bertujuan untuk mengetahui tingkat kejadian infeksi tb dan faktor-faktor risiko apa saja yang berpengaruh terhadap kejadian infeksi TB laten.
Metode. Penelitian ini merupakan bagian dari riset operasional tuberkulosis group (TORG) tahun 2015/2016 di Rutan kelas I, Bandung, Jawa Barat. Penelitian ini menggunakan metode survey cross-sectional. Subyek pada penelitian adalah WBP yang mendiami Rutan kelas I Bandung. Subject WBP dipilih dengan cara systematic random sampling. Skrining latent TB dilakukan dengan menggunakan Tuberculine Skin Test (TST) dilakukan pada semua subyek. Skrining TB dilakukan dengan pemeriksaan foto toraks. Subyek dengan gejala TB dan/ atau foto toraks sugestive TB dimintakan sputum untuk pemeriksaan basil tahan asam (BTA), xpert Mtb/Rif. Informasi mengenai faktor resiko dikumpulkan dengan wawancara dan pemeriksaan kondisi lingkungan.
Hasil. Dari 400 orang WBP terpilih, 4 orang mempunyai riwayat TB sebelumnya dan pemeriksaan tidak dilanjutkan. Dari 396 WBP semuanya adalah laki-laki, median dan rentang usia subyek adalah 31 (18 s/d 67) tahun, dengan median dan rentang masa pidana 1.125 (0 s/ 18) tahun. WBP yang baru pertama kali penahanan adalah sejumlah 16 (48,6%). Sebanyak 58 (14,8%) WBP tidak TB, 194(49%) mengalami infeksi TB laten, 128(32,3%) tb terduga, 7(1,8%) TB klinis, dan 9(2,3%) TB terkonfirmasi. Kejadian laten tb cenderung lebih tinggi pada WBP dengan masa penahanan > 3 bulan daripada yang < 3 bulan yaitu dan 48.3% dan 40.4% berturutan, Riwaya merokok juga ditemukan berkorelasi dengan kejadian infeksi TB laten. Kesimpulan. Angka kejadian TB laten ditemukan tinggi di Lapas dan menunjukkan kecenderungan makin tinggi dengan lamanya penahanan. Angka kejadian TB juga ditemukan 3 kali lipat dibandingkan dengan di populasi. Temuan ini menunjukkan besarnya permasalahan tb di lapas dan perlunya perhatian lebih tinggi untuk pengendaliannya. Silahkan Unduh Disini!

Spatial Analysis of Dengue Hemoraghic Fever (DHF) in Coastal Area, Kendari City, South-East Sulawesi, Indonesia

Asyary, Al

Background. DHF mitigation still becoming global problems, especially in coastal area. Although the health paradigm exchange have been initiate in Indonesia which is curative becomes preventif action, it is not decreasing the DHF prevalence in Kendari City yet.
Objectives. This study aims to find distribution of DHF disease related to population density and health provider accessibility.
Methods. 156 DHF cases was collected in 2008 at Kendari City primary data as a coastal area in Indonesia. A buffering and overlay spatial analysis as descriptives study design was held to define a real-world perspectives.
Results. There are 12 health centers and 7 hospitals whose service 10 sub-districts (Kecamatan) in Kendari City. Thematics mapping describes that distribution pattern of DHF diseases randomized on health facilities. DHF cases are randomized of all su-districts. But, these cases are clustered with 335 live/km2 population density on coastal teritory. Health provider accessibility representatives on 100.000 populations was counted with 750 metres buffering analysis. This results 3 health centers are not accessible to DHF cases.
Conclusions. Pattern of distribution DHF cases in Kendari City happen broadly in coastal teritory. Coastal teritory which near of beach have bigger population than other teritories with crowded density. Aedes aegypty sp. as a principal factors is related to coastal determinants on this finding research.

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Computerized Physician Order Entry (CPOE) on Prescribing at GMC Health Center, Yogyakarta: A Case Study

Asyary, Al

In major of its applying, CPOE has been shown to improve patient safety by reducing medication errors and subsequent adverse drug events (ADEs). Medication error such as elixir in writing, determination of dose and correct drug type use at patient with the certain health condition in health service can be depressed. But, and so do own the negative impact. One of them is the existence of time addition in entry of patient information by physician which is potential event for being an error(s) on prescribing activity. The goal was to describe the CPOE on prescribing, also as known as electronic prescribing, in academic health facility of GMC Health Center. This case study design, depth interview and observation was conducted in academic healthcare facility GMC Health Center. The subject was physician and farmacist as end-user of CPOE system on presribing. From interview guide and check list observation tools was obtained that CPOE in GMC Health Center have influenced by some principles from existing themes. Ease of use and usefullness perceptions had been change end-user’s mind about implementation of this systems.

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TEEN RELIGIUSITY: CASE STUDY IN TEENS IN SURABAYA,
MATARAM AND KENDARI

Hamid Al Jufri, Jufri

This research is motivated by concerns about the problems of teenagers who are
heavily involved in free sex, drugs, alcohol, brawl and pornography. This condition is
certainly not stand alone many factors that mempengeruhinya, family, community
and school. This study attempts to describe the level of adolescent religiosity in
Surabaya, Mataram and Kendari, what factors predominate and how strategies
improve and increase adolescent religiosity.
From the results of the research conducted from May to October 2013, it was found
that the level of adolescent religiosity in the three study cities was at a very high
level. There is no significant difference between adolescent religiosity in Surabaya,
Mataram and Kendari. In the aspect of youth religious knowledge in Surabaya is
relatively better than adolescents in Mataram and Kendari, the religious attitudes
aspect of adolescents in Mataram is relatively better than adolescents in Surabaya
and Kendari, and the moral aspect of religious (akhlakul karimah) adolescents in
Mataram is relatively better than adolescents in Kendari and Surabaya.
Religious conditions in the families in these three study cities are at good level
(conducive), there is no significant difference between one city and another.
Indicators of religious adherence of parents and habituation cultivate religious
values in the family in Mataram lebik both daripda in Surabaya and Kendari. The
socio-religious level of society is at a fairly good level (conducive), there are
significant differences in the three cities. In the city of Mataram it is better the social
level of the religious community than in Surabaya and Kendari. The condition of
religious education in schools is at a fairly good level, and there is no significant
difference between the codes in the three study cities. In the aspect of availability of
religious facilities and intensity of religious execution activities in Mataram city is
relatively better than in Surabaya and Kendari.
The dominant factors influencing the religiosity of adolescents in Surabaya, Mataram
and Kendari are religious education factors in school and religion in the family.
Socio-socio-cultural factors become the determinants of youth religiosity in Mataram
and supporting factors for adolescents in Surabaya and Kendari. It means to produce
religious teenagers need attention from family, school and community. However,
families and schools have not been able to portray themselves as character bulding
places.
The fact that families and schools have not played a significant role in the formation
of adolescent religiosity is evidence of failure or dysfunctional families and schools
as character bulding actors. To that end, the need to improve the ability of families
and schools in various aspects and areas as proposed in the quality improvement
strategy of family, school and community.

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THE PRACTICE OF E-LEARNING BASED LEARNING MANAGEMENT

Hamid Al Jufri, Jufri

This study aims to create a learning management model based on e-learning in the context of improving the quality of e-based learning which is now less manageable. E-learning based learning management is profoundly potential to make the learning process more effective for both students and teachers significantly in terms of place, time and cost. This research was conducted by using quantitative approach. Statistical testing of the t-test at a = 0.05 (95% significance level) is employed to compare learning outcomes between the experimental groups. The results showed that such e-learning based learning model helps students in learning and acquires learning outcomes significantly higher, that is (P> 0.95) compared with students studying with conventional learning. E-learning model improves the effectiveness of lecture’s performance of faculty and students’ achievement due to the utilization of more efficient space, time, cost, and energy. Thereby, e-learning based learning model is effective to improve the quality of teaching and learning as a whole.

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Student’s learning: Instrumentally, Integratively or Personally Motivated?

Fitriani, Somariah

The study focuses on learners’ motivation to learn English as
L2/foreign language. For data collection, questionnaire was distributed
to 82 respondents of STIBA IEC Jakarta via whatsApp and face book
messenger. In addition, interviews were also conducted to find out the
detail information about the role of teacher and
inspirational/motivational teacher. For data analysis, the step of
sorting, classifying, coding, and presenting the data and drawing
conclusion was adopted. This is a research based article, which has
aimed to elaborate the learners’ English learning motivation whether it
is instrumentally, integratively or personally motivated and the most
dominance type of motivation as well as the important role of teacher in
motivating students. It is somewhat surprising that there are six
categories found in the research, namely personal motivation (PS),
integrative motivation (IT), instrumental motivation (IS), the
combination of PS & IT, PS & IS, and IT & IS. The findings have
revealed that 1) instrumental motivation is the most dominant type as
the first rank, which includes to get a better living, better jobs and
position; PS & IS as second rank, IT & IS as the third rank, PS & IT as
the fourth rank, personal motivation as the fifth rank and integrative
motivation as the last rank; 2) teacher who is resourceful, skillful,
competent and has good personality plays a imperative role in
motivating and inspiring students. To sum up, regardless of personal,
integrative or instrumental motivation, teacher as a role model also
determines learner’s success in learning L2.

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http://dx.doi.org/10.18326/rgt.v10i2.140-156

Simultaneous Analytical Method Of 6-Mercaptopurine and 6-
Methylmercaptopurine In-vitro Study With Bio-Sampling
Venipuncture and Dried Blood Spot

Supandi, Supandi

Objective: 6-Mercaptopurine (6-MP) is a cancer chemotherapeutic agent. Metabolic pathway by
thiopurine S-methyltransferase (TPMT) to become 6-methylmercaptopurine (6-MMP).Bio-sampling is
required to obtainbiological sample, using two technique; invasive (venipuncture) and minimum
invasive(dried blood spot). This study aims to obtain an optimization and validation analysis 6-MP and
6-MMP in vitro study with bio-sampling venipuncture and dried blood spot (DBS). Method: Plasma from
venipuncture method extraction was done using dichloromethane. Separation was performed using
Waters HPLC, C18 SunfireTM column (5μm, 250 x 4.6 mm), with gradient elution, flow rate 1 mL/min
and detected at UV-PDA wavelength of 303 nm. Bio-sampling dried blood spot with DBS CAMAG®
paper diameter of 8 mm and extracted with acetonitrile-methanol (1:3). Separation was performed with
Waters LC-MS/MS UPLC C18 column (1.7 μm, 2.1 x 100 mm) with gradient elution, flow rate 0.2
mL/min. 5-fluorouracil (5-FU) was used as internal standard.Result: The method venipuncture was
linear at concentration range of 2-200 ng/mL for 6-MP and 20-2000 ng/mL for 6-MMP. The method dried
blood spot using Waters Xevo TQD for mass detection with positive electrospray ionization (ESI) for 6-
MP, 6-MMP and negative ESI for 5-FU in Multiple Reaction Monitoring mode. Linear with the range 26-
1000 ng/mL for 6-MP and 13-500 ng/mL for 6-MMP.Conclusion: The developed method is valid for 6-MP
and 6-MMP simultaneously in vitro from venipuncture using HPLC and from dried blood spot using LCMS/MS
and showed good selectivity, linearity, accuracy and precision, matrix effect and stability.

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SIMULTANEOUS ANALYTICAL METHOD DEVELOPMENT OF 6-MERCAPTOPURINE AND
6-METHYLMERCAPTOPURINE IN DRIED BLOOD SPOT USING ULTRA PERFORMANCE LIQUID
CHROMATOGRAPHY TANDEM MASS SPECTROMETRY

Supandi, Supandi

Objective: 6-mercaptopurine (6-MP) is a chemotherapeutic agent in the antimetabolite class. It has to go through the metabolic pathway to form
6-methyl MP (6-MMP). This study aimed to obtain an optimum and validated method for the analysis of 6-MP and 6-MMP in dried blood spot (DBS)
samples simultaneously and to evaluate the potential for future drug concentration monitoring in DBS samples.
Methods: The quality control and calibration curves were made by spotting 40 µL blood on DBS paper and dried for 3 hrs. DBS papers were cut with a
diameter of 8 mm and extracted with acetonitrile-methanol (1:3) containing internal standard 5-fluorouracil (5-FU). Separation was performed with
waters acquity ultra performance liquid chromatography BEH C18 column of 1.7 μm (2.1×100 mm) with a mobile phase consisting of 0.1% formic
acid in water 0.1% formic acid in acetonitrile with gradient elution and a flow rate of 0.2 mL/minute. Mass detection was performed using Waters
Xevo TQD with positive electrospray ionization (ESI) for 6-MP and 6-MMP and negative ESI for 5-FU in the multiple reaction monitoring mode.
Results: The detection rates of 6-MP, 6-MMP, and 5-FU were 153.09>119.09, 167.17>126.03, and 129.09>42.05, respectively. This method was linear
with the range at 26-1000 ng/mL for 6-MP and 13-500 ng/mL for 6-MMP with consecutive r≥0.998 and ≥0.999, respectively. The % relative error
value and % relative standard deviation for accuracy and precision of intraday and interday were not more than 15% and not more than 20% at the
lower limit of quantification concentration, respectively.
Conclusions: This method fulfilled the requirements of selectivity, linearity, carry over, and matrix effects referring to the European Medicines Agency
guidelines.

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RELIGIOUS HARMONY IN INDONESIA
(Learning Harmony and Religious
Tolerance of Kampung Sawah Society In
Bekasi City)

Wahjusaputri, Sintha

Wahjusaputri, SinthadanFitriani, Somariah RELIGIOUS HARMONY IN INDONESIA (Learning Harmony and Religious Tolerance of Kampung Sawah Society In Bekasi City). In: Prosiding Kolokium Doktor dan Seminar Hasil Penelitian Hibah Tahun 2016.

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Human Integration of a Character-based
Curriculum and Humanistic Values As Basic
Initiation of a Human Rights-friendly School

Wahjusaputri, Sintha

Wahjusaputri, Sintha Human Integration of a Character-based Curriculum and Humanistic Values As Basic Initiation of a Human Rights-friendly School. In: ISLLE 2017 The 1st International Seminar on Language, Literature and Education.

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